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Tumor necrosis factor alpha (TNF-α) is produced by neutrophils, activated lymphocytes, macrophages, NK cells, LAK cells, astrocytes endothelial cells, smooth muscle cells and some transformed cells. TNF-α occurs as a secreted, soluble form and as a membrane-anchored form, both of which are biologically active. The naturally-occurring form of TNF-α is glycosylated, but non-glycosylated recombinant TNF-α has comparable. The biologically active native form of TNF--α is reportedly a trimer. Human and murine TNF-? show approximately 79% homology at the amino acid level and cross reactivity between the two species. Two types of receptors for TNF--α have been described and virtually all cell types studied show the presence of one or both of these receptor types.
货号 | 103-01H |
产地 | 美国 |
缩写 | rhTNF--His |
规格 | 10ug |
用途 | 科研 |
储存 | -20度 |
运输 | 干冰 |
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