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BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta of signaling proteins and were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Reduction in BMP-4 expression is associated with a number of bone- related diseases, including Fibrodysplasia Ossificans Progressiva. BMP-4 is synthesized as large precursor molecule which are cleaved by proteolytic enzymes. The active form can be found as homodimers or heterodimers.
货号 | 108-04 |
产地 | 美国 |
缩写 | rhBMP-4 |
规格 | 2ug |
用途 | 科研 |
储存 | -20度 |
运输 | 干冰 |
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