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Fibroblast growth factor 21 (FGF-21) belongs to the large FGF family which has at least 23 members. However, FGF-21, along with FGF-19 and FGF-23, belongs to a subfamily of atypical FGFs where it lacks a conventional heparin-binding motif. In the presence of β Klotho as a cofactor, FGF-21 signals via the FGFR1c and 4 receptors to induce glucose uptake by adipocytes. This novel metabolic regulator acts as an endocrine hormone and is predominantly produced in liver upon the induction of peroxisome proliferator-activator receptors, PPAR α and PPAR α.
货号 | 104-21 |
产地 | 美国 |
缩写 | rhFGF-21 |
规格 | 5ug |
用途 | 科研 |
储存 | -20度 |
运输 | 干冰 |
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