重组人骨形成蛋白-2 rhBMP-2
Recombinant Human Bone Morphogenetic Protein-2, 2 ug
品牌：
ScienCell
货号：
108-02
价格：
$95
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BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta of signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 is also involved in organogenesis, particularly in cardiac morphogenesis, as well as limb bud formation. BMP-2 expression can be found in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine.The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease.
| 货号 | 108-02 |
| 产地 | 美国 |
| 缩写 | rhBMP-2 |
| 规格 | 2ug |
| 用途 | 科研 |
| 储存 | -20度 |
| 运输 | 干冰 |
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