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BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta of signaling
proteins and were originally identified as protein regulators of
cartilage and bone formation. However, they have since been shown to be
involved in embryogenesis and morphogenesis of various tissues and
organs. BMPs have also been shown to regulate the growth,
differentiation, chemotaxis and apoptosis of various cell types,
including mesenchymal cells, epithelial cells, hematopoietic cells and
neuronal cells. Reduction in BMP-4 expression is associated with a
number of bone- related diseases, including Fibrodysplasia Ossificans
Progressiva. BMP-4 is synthesized as large precursor molecule which are
cleaved by proteolytic enzymes. The active form can be found as
homodimers or heterodimers.
货号 | 108-04 |
产地 | 美国 |
缩写 | rhBMP-4 |
规格 | 2 μg |
用途 | 科研 |
储存 | -20度 |
运输 | 干冰 |
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